congopound8

80, 95%CI 0.67-0.97; P = 0.021). With regard to refined grain consumption, 13 studies were included. The overall multi-variable adjusted RR indicated that refined grain consumption was positively associated with MetS (RR = 1.37, 95%CI 1.02-1.84; P = 0.036). Conclusions The existing evidence suggests that whole grain consumption is negatively associated with MetS, whereas refined grain consumption is positively associated with MetS. Our result might be helpful to better consider the diet effect on MetS. However, more well-designed prospective cohort studies are needed to elaborate the concerned issues further.The use of extensive questionnaires has the limitation of filling time bias, related to the ability to focus and accurately respond to many items, justifying the necessity for a brief version. This study aimed to build a brief version of the Caffeine Expectancy Questionnaire in Brazil (B-CaffEQ-BR) composed of 21 items divided into seven factors, with as adequate consistency and reproducibility as the full version. Quantitative procedures using statistical modeling were applied using the CaffEQ-BR (full version) database keeping the Mean Absolute Error (MAE) (based on the full version) less then 0.5 and Cronbach's α and Intraclass Correlation Coefficient (ICC) ≥0.7. The expert panel (n = 3), in a blind design, evaluated the semantic structuring within the options indicated by previous statistical modeling until the agreement of the expert panel. The participants (n = 62), Brazilian adults who were regular caffeine consumers (175.8 ± 94.4 mg/day), of whom 62.9% were women, 33.1 ± 9.7 years, 24.5 ± 3.8 kg/m2, and 62.9% of whom self-identified as white, were asked to respond twice to the online questionnaire in 48-72 h. The first sample (n = 40) tested interobserver reproducibility with the double application of B-CaffEQ-BR. Another sample (n = 22) answered the CaffEQ-BR (full version) and B-CaffEQ-BR, and the last sample (n = 18) performed the reverse process. The B-CaffEQ-BR presented excellent internal consistency (Cronbach's α ≥ 0.729) and overall reproducibility (ICC ≥ 0.915) for the entire questionnaire and its seven factors. The B-CaffEQ-BR can be a valuable tool in caffeine research with the Brazilian adult population.Water scarcity and excess adiposity are two of the main problems worldwide and in Mexico, which is the most obese country in the world and suffers from water scarcity. Food production represents 90% of a person's water footprint (WF), and healthy diets can lead to less WF than do unhealthy diets related to obesity. We calculated the WF of the diet and caloric intake of adults in Mexico and analyzed its relationship with adiposity. Also, the risk of water expenditure due to adiposity and adherence to dietary recommendations regarding WF of international healthy diets were examined. A Food Consumption Frequency Questionnaire (FCFQ) was applied to 395 adults. Body mass index (BMI), associated with adiposity indicators, was used as a reference for grouping a sample into adiposity levels. The WF was calculated according to the WF Assessment Method, considering correction factors and accounting for water involved in cooking and food washing. Our results showed that the Mexican diet spends 6,056 liters per person per day (L p-1d-1) and is 55% higher than international healthy diets WF. Consumption of beef, milk, fruits, chicken, and fatty cereals represented 56% of total WF. Strong relations appeared between hypercaloric diets and high WF. Diets of people with excess adiposity generated statistically higher WF with extra expenses of 729 L p-1d-1 compared with the normal adiposity population. Following nutritional recommendations offers a protective factor in water care, whereas not adhering to these represents a risk up to 93 times greater of water expenditure regarding international healthy diets. Therefore, both for the general population and to regulate obesity, adequate diets can help mitigate the problem of water scarcity.Background It is well-established that the etiology of type 2 diabetes differs between individuals. Insulin resistance (IR) may develop in different tissues, but the severity of IR may differ in key metabolic organs such as the liver and skeletal muscle. Recent evidence suggests that these distinct tissue-specific IR phenotypes may also respond differentially to dietary macronutrient composition with respect to improvements in glucose metabolism. Objective The main objective of the PERSON study is to investigate the effects of an optimal vs. suboptimal dietary macronutrient intervention according to tissue-specific IR phenotype on glucose metabolism and other health outcomes. Methods In total, 240 overweight/obese (BMI 25 – 40 kg/m2) men and women (age 40 – 75 years) with either skeletal muscle insulin resistance (MIR) or liver insulin resistance (LIR) will participate in a two-center, randomized, double-blind, parallel, 12-week dietary intervention study. At screening, participants undergo a 7-point oral glued on IR phenotype. The results of the PERSON study will contribute knowledge on the effectiveness of targeted nutritional strategies to the emerging field of precision nutrition, and improve our understanding of the complex pathophysiology of whole body and tissue-specific IR. Clinical Trial Registration https//clinicaltrials.gov/ct2/show/NCT03708419, clinicaltrials.gov as NCT03708419.Background and Purpose The results regarding the independent association between homocysteine (Hcy) levels and post-stroke cognitive impairment (PSCI) were inconsistent. The effect of age on this association has yet to be explored. This study aims to determine the relationship between Hcy levels, age, and cognitive impairment in a post-stroke population. Methods A total of 592 patients with acute ischemic stroke (AIS) completed follow-up. GI254023X manufacturer Serum Hcy levels were measured enzymatically by spectrophotometry within 24 h of admission. Cognitive function was evaluated by the Mini-Mental State Examination (MMSE) 1 month after stroke, and the scores ≤ 24 were considered as cognitive impairment. Our study was dichotomized into two groups by a cut-off of 65 years. Multivariate logistic regression models were used to determine the association between baseline Hcy levels and cognitive impairment. Results According to the MMSE score, 317 (53.5%) patients had cognitive impairment. Patients with higher levels of Hcy were more prone to have cognitive impairment 1 month after stroke than patients with lower levels of Hcy (p less then 0.